Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase

Histone H3 phosphorylation is the hallmark of mitosis deposited by aurora kinase B. Benzo[e]pyridoindoles are a family of potent, broad, ATP-competitive aurora kinase inhibitors. However, benzo[e]pyridoindole C4 only inhibits histone H3 phosphorylation in prophase but not in metaphase. Under the C4...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Ly-Thuy-Tram, Vu, Hong-Lien, Nguyen, Chi-Hung, Molla, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625866/
https://www.ncbi.nlm.nih.gov/pubmed/23616922
http://dx.doi.org/10.1242/bio.20133079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625866/
https://www.ncbi.nlm.nih.gov/pubmed/23616922
http://dx.doi.org/10.1242/bio.20133079

Ejemplares similares