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A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma

Melanoma patients with BRAF mutations respond to treatment with vemurafenib, thus creating a need for accurate testing of BRAF mutation status. We carried out a blinded study to evaluate various BRAF mutation testing methodologies in the clinical setting. Formalin-fixed, paraffin-embedded melanoma s...

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Detalles Bibliográficos
Autores principales: Richter, Anna, Grieu, Fabienne, Carrello, Amerigo, Amanuel, Benhur, Namdarian, Kateh, Rynska, Aleksandra, Lucas, Amanda, Michael, Victoria, Bell, Anthony, Fox, Stephen B., Hewitt, Chelsee A., Do, Hongdo, McArthur, Grant A., Wong, Stephen Q., Dobrovic, Alexander, Iacopetta, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625889/
https://www.ncbi.nlm.nih.gov/pubmed/23584600
http://dx.doi.org/10.1038/srep01659