Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment

There is evidence that naturally occurring antibodies directed against Aβ (nAbs-Aβ) have a role in Aβ-metabolism and Aβ-clearance. The presence of nAbs-Aβ leads to a reduction in amyloid fibrillation and thus a reduction in their toxicity. We investigated the effects of nAbs-Aβ in respect to oligome...

Descripción completa

Detalles Bibliográficos
Autores principales: Mengel, D, Röskam, S, Neff, F, Balakrishnan, K, Deuster, O, Gold, M, Oertel, W H, Bacher, M, Bach, J-P, Dodel, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625912/
https://www.ncbi.nlm.nih.gov/pubmed/23462987
http://dx.doi.org/10.1038/tp.2012.151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625912/
https://www.ncbi.nlm.nih.gov/pubmed/23462987
http://dx.doi.org/10.1038/tp.2012.151

Ejemplares similares