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Metabolic effects of sapropterin treatment in autism spectrum disorder: a preliminary study

Sapropterin, a synthetic form of tetrahydrobiopterin (BH(4)), has been reported to improve symptoms in children with autism spectrum disorder (ASD). However, as BH(4) is involved in multiple metabolic pathway that have been found to be dysregulated in ASD, including redox, pterin, monoamine neurotra...

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Detalles Bibliográficos
Autores principales: Frye, R E, DeLaTorre, R, Taylor, H B, Slattery, J, Melnyk, S, Chowdhury, N, James, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625913/
https://www.ncbi.nlm.nih.gov/pubmed/23462988
http://dx.doi.org/10.1038/tp.2013.14