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Deletion of pic results in decreased virulence for a clinical isolate of Shigella flexneri 2a from China
BACKGROUND: Shigella is a major pathogen responsible for bacillary dysentery, a severe form of shigellosis. Severity of the disease depends on the virulence of the infecting strain. Shigella pathogenicity is a multi-gene phenomenon, involving the participation of genes on an unstable large virulence...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626585/ https://www.ncbi.nlm.nih.gov/pubmed/23391153 http://dx.doi.org/10.1186/1471-2180-13-31 |