Hybrid Approach for Predicting Coreceptor Used by HIV-1 from Its V3 Loop Amino Acid Sequence

BACKGROUND: HIV-1 infects the host cell by interacting with the primary receptor CD4 and a coreceptor CCR5 or CXCR4. Maraviroc, a CCR5 antagonist binds to CCR5 receptor. Thus, it is important to identify the coreceptor used by the HIV strains dominating in the patient. In past, a number of experimen...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Ravi, Raghava, Gajendra P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626595/
https://www.ncbi.nlm.nih.gov/pubmed/23596523
http://dx.doi.org/10.1371/journal.pone.0061437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626595/
https://www.ncbi.nlm.nih.gov/pubmed/23596523
http://dx.doi.org/10.1371/journal.pone.0061437

Ejemplares similares