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Inverse expression of hyaluronidase 2 and hyaluronan synthases 1–3 is associated with reduced hyaluronan content in malignant cutaneous melanoma
BACKGROUND: Hyaluronan is an extracellular matrix glycosaminoglycan involved in invasion, proliferation and metastasis of various types of carcinomas. In many cancers, aberrant hyaluronan expression implicates disease progression and metastatic potential. Melanoma is an aggressive skin cancer. The r...
Autores principales: | Hanna, Siiskonen, Mari, Poukka, Kristiina, Tyynelä-Korhonen, Reijo, Sironen, Sanna, Pasonen-Seppänen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626669/ https://www.ncbi.nlm.nih.gov/pubmed/23560496 http://dx.doi.org/10.1186/1471-2407-13-181 |
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