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A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina

Widespread gene delivery to the retina is an important challenge for the treatment of retinal diseases, such as retinal dystrophies. We and others have recently shown that the intravenous injection of a self-complementary (sc) AAV9 vector can direct efficient cell transduction in the central nervous...

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Detalles Bibliográficos
Autores principales: Bemelmans, Alexis-Pierre, Duqué, Sandra, Rivière, Christel, Astord, Stéphanie, Desrosiers, Mélissa, Marais, Thibault, Sahel, José-Alain, Voit, Thomas, Barkats, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626698/
https://www.ncbi.nlm.nih.gov/pubmed/23613884
http://dx.doi.org/10.1371/journal.pone.0061618