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GSA-PCA: gene set generation by principal component analysis of the Laplacian matrix of a metabolic network

BACKGROUND: Gene Set Analysis (GSA) has proven to be a useful approach to microarray analysis. However, most of the method development for GSA has focused on the statistical tests to be used rather than on the generation of sets that will be tested. Existing methods of set generation are often overl...

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Detalles Bibliográficos
Autores principales: Jacobson, Dan, Emerton, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626710/
https://www.ncbi.nlm.nih.gov/pubmed/22876834
http://dx.doi.org/10.1186/1471-2105-13-197