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Human single-stranded DNA binding proteins are essential for maintaining genomic stability
The double-stranded conformation of cellular DNA is a central aspect of DNA stabilisation and protection. The helix preserves the genetic code against chemical and enzymatic degradation, metabolic activation, and formation of secondary structures. However, there are various instances where single-st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626794/ https://www.ncbi.nlm.nih.gov/pubmed/23548139 http://dx.doi.org/10.1186/1471-2199-14-9 |