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Human single-stranded DNA binding proteins are essential for maintaining genomic stability

The double-stranded conformation of cellular DNA is a central aspect of DNA stabilisation and protection. The helix preserves the genetic code against chemical and enzymatic degradation, metabolic activation, and formation of secondary structures. However, there are various instances where single-st...

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Detalles Bibliográficos
Autores principales: Ashton, Nicholas W, Bolderson, Emma, Cubeddu, Liza, O’Byrne, Kenneth J, Richard, Derek J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626794/
https://www.ncbi.nlm.nih.gov/pubmed/23548139
http://dx.doi.org/10.1186/1471-2199-14-9