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Evidence of recent natural selection on the Southeast Asian deletion (--(SEA)) causing α-thalassemia in South China
BACKGROUND: The Southeast Asian deletion (--(SEA)) is the most commonly observed mutation among diverse α-thalassemia alleles in Southeast Asia and South China. It is generally argued that mutation --(SEA), like other variants causing hemoglobin disorders, is associated with protection against malar...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626844/ https://www.ncbi.nlm.nih.gov/pubmed/23497175 http://dx.doi.org/10.1186/1471-2148-13-63 |