Cargando…
Chromosomal evolution of Escherichia coli for the efficient production of lycopene
BACKGROUND: Plasmid-based overexpression of genes has been the principal strategy for metabolic engineering. However, for biotechnological applications, plasmid-based expression systems are not suitable because of genetic instability, and the requirement for constant selective pressure to ensure pla...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626847/ https://www.ncbi.nlm.nih.gov/pubmed/23356604 http://dx.doi.org/10.1186/1472-6750-13-6 |