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Chromosomal evolution of Escherichia coli for the efficient production of lycopene

BACKGROUND: Plasmid-based overexpression of genes has been the principal strategy for metabolic engineering. However, for biotechnological applications, plasmid-based expression systems are not suitable because of genetic instability, and the requirement for constant selective pressure to ensure pla...

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Detalles Bibliográficos
Autores principales: Chen, Yun-Yan, Shen, Hong-Jie, Cui, Yan-Yan, Chen, Shang-Guang, Weng, Zhi-Ming, Zhao, Ming, Liu, Jian-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626847/
https://www.ncbi.nlm.nih.gov/pubmed/23356604
http://dx.doi.org/10.1186/1472-6750-13-6