Cargando…

Detecting recurrent gene mutation in interaction network context using multi-scale graph diffusion

BACKGROUND: Delineating the molecular drivers of cancer, i.e. determining cancer genes and the pathways which they deregulate, is an important challenge in cancer research. In this study, we aim to identify pathways of frequently mutated genes by exploiting their network neighborhood encoded in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Babaei, Sepideh, Hulsman, Marc, Reinders, Marcel, Ridder, Jeroen de
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626877/
https://www.ncbi.nlm.nih.gov/pubmed/23343428
http://dx.doi.org/10.1186/1471-2105-14-29