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Drugging Hedgehog: signaling the pathway to translation

First discovered in Drosophila, the Hedgehog signaling pathway controls a wide range of developmental processes and is implicated in a variety of cancers. The success of a screen for chemical modulators of this pathway, published in 2002, opened a new chapter in the quest to translate the results of...

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Detalles Bibliográficos
Autores principales: Carney, Tom J, Ingham, Philip W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626896/
https://www.ncbi.nlm.nih.gov/pubmed/23587183
http://dx.doi.org/10.1186/1741-7007-11-37