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Drugging Hedgehog: signaling the pathway to translation
First discovered in Drosophila, the Hedgehog signaling pathway controls a wide range of developmental processes and is implicated in a variety of cancers. The success of a screen for chemical modulators of this pathway, published in 2002, opened a new chapter in the quest to translate the results of...
Autores principales: | Carney, Tom J, Ingham, Philip W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626896/ https://www.ncbi.nlm.nih.gov/pubmed/23587183 http://dx.doi.org/10.1186/1741-7007-11-37 |
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