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Cilia, tubby mice, and obesity

Primary cilia have been previously linked to the central regulation of satiety. The tubby mouse is characterized by maturity-onset obesity and blindness. A recent paper demonstrates molecular defects in trafficking of ciliary GPCRs in the central neurons of tubby mice, underscoring the role of cilia...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Saikat, Jackson, Peter K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626941/
https://www.ncbi.nlm.nih.gov/pubmed/23351214
http://dx.doi.org/10.1186/2046-2530-2-1