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The role of astrocytes in CNS tumors: pre-clinical models and novel imaging approaches

Brain metastasis is a significant clinical problem, yet the mechanisms governing tumor cell extravasation across the blood-brain barrier (BBB) and CNS colonization are unclear. Astrocytes are increasingly implicated in the pathogenesis of brain metastasis but in vitro work suggests both tumoricidal...

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Detalles Bibliográficos
Autores principales: O'Brien, Emma R., Howarth, Clare, Sibson, Nicola R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627137/
https://www.ncbi.nlm.nih.gov/pubmed/23596394
http://dx.doi.org/10.3389/fncel.2013.00040