Cargando…

Lipid-II forms potential “landing terrain” for lantibiotics in simulated bacterial membrane

Bacterial cell wall is targeted by many antibiotics. Among them are lantibiotics, which realize their function via interaction with plasma membrane lipid-II molecule — a chemically conserved part of the cell wall synthesis pathway. To investigate structural and dynamic properties of this molecule, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Chugunov, Anton, Pyrkova, Darya, Nolde, Dmitry, Polyansky, Anton, Pentkovsky, Vladimir, Efremov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627190/
https://www.ncbi.nlm.nih.gov/pubmed/23588060
http://dx.doi.org/10.1038/srep01678