Cargando…

Acute sensitivity of the oral mucosa to oncogenic K-ras

Mouse models of cancer represent powerful tools for analysing the role of genetic alterations in carcinogenesis. Using a mouse model that allows tamoxifen-inducible somatic activation (by Cre-mediated recombination) of oncogenic K-ras(G12D) in a wide range of tissues, we observed hyperplasia of squa...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Weyden, Louise, Alcolea, Maria P, Jones, Philip H, Rust, Alistair G, Arends, Mark J, Adams, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627303/
https://www.ncbi.nlm.nih.gov/pubmed/21381032
http://dx.doi.org/10.1002/path.2853