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Iso-seco-tanapartholides: Isolation, Synthesis and Biological Evaluation

The isolation, identification and total synthesis of two plant-derived inhibitors of the NF-κB signaling pathway from the iso-seco-tanapartholide family of natural products is described. A key step in the efficient reaction sequence is a late-stage oxidative cleavage reaction that was carried out in...

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Detalles Bibliográficos
Autores principales: Makiyi, Edward F, Frade, Raquel F M, Lebl, Tomas, Jaffray, Ellis G, Cobb, Susan E, Harvey, Alan L, Slawin, Alexandra M Z, Hay, Ronald T, Westwood, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627315/
https://www.ncbi.nlm.nih.gov/pubmed/23606807
http://dx.doi.org/10.1002/ejoc.200901016