Fangchinoline induces G0/G1 arrest by modulating the expression of CDKN1A and CCND2 in K562 human chronic myelogenous leukemia cells

Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease caused by the oncoprotein BCR-ABL, which exhibits a constitutive tyrosine kinase activity. Imatinib mesylate (IM), an inhibitor of the tyrosine kinase activity of BCR-ABL, has been used as a first-line therapy for CML. However, IM i...

Descripción completa

Detalles Bibliográficos
Autores principales: WANG, YUPING, CHEN, JIE, WANG, LIN, HUANG, YUJI, LENG, YE, WANG, GUIYING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627453/
https://www.ncbi.nlm.nih.gov/pubmed/23596478
http://dx.doi.org/10.3892/etm.2013.924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627453/
https://www.ncbi.nlm.nih.gov/pubmed/23596478
http://dx.doi.org/10.3892/etm.2013.924

Ejemplares similares