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A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells

Growth and differentiation of multicellular systems is orchestrated by spatially restricted gene expression programs in specialized subpopulations. The targeted manipulation of such processes by synthetic tools with high-spatiotemporal resolution could, therefore, enable a deepened understanding of...

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Detalles Bibliográficos
Autores principales: Müller, Konrad, Engesser, Raphael, Metzger, Stéphanie, Schulz, Simon, Kämpf, Michael M., Busacker, Moritz, Steinberg, Thorsten, Tomakidi, Pascal, Ehrbar, Martin, Nagy, Ferenc, Timmer, Jens, Zubriggen, Matias D., Weber, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627562/
https://www.ncbi.nlm.nih.gov/pubmed/23355611
http://dx.doi.org/10.1093/nar/gkt002