Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats

Targeted genome engineering requires nucleases that introduce a highly specific double-strand break in the genome that is either processed by homology-directed repair in the presence of a homologous repair template or by non-homologous end-joining (NHEJ) that usually results in insertions or deletio...

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Detalles Bibliográficos
Autores principales: Gabsalilow, Lilia, Schierling, Benno, Friedhoff, Peter, Pingoud, Alfred, Wende, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627573/
https://www.ncbi.nlm.nih.gov/pubmed/23408850
http://dx.doi.org/10.1093/nar/gkt080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627573/
https://www.ncbi.nlm.nih.gov/pubmed/23408850
http://dx.doi.org/10.1093/nar/gkt080

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