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Low-level processing of Illumina Infinium DNA Methylation BeadArrays

We propose a novel approach to background correction for Infinium HumanMethylation data to account for technical variation in background fluorescence signal. Our approach capitalizes on a new use for the Infinium I design bead types to measure non-specific fluorescence in the colour channel opposite...

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Detalles Bibliográficos
Autores principales: Triche, Timothy J., Weisenberger, Daniel J., Van Den Berg, David, Laird, Peter W., Siegmund, Kimberly D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627582/
https://www.ncbi.nlm.nih.gov/pubmed/23476028
http://dx.doi.org/10.1093/nar/gkt090