DNA-recognition process described by MD simulations of the lactose repressor protein on a specific and a non-specific DNA sequence

The lactose repressor protein may bind DNA in two possible configurations: a specific one, if the DNA sequence corresponds to a binding site, and a non-specific one otherwise. To find its target sequences, the lactose repressor first binds non-specifically to DNA, and subsequently, it rapidly search...

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Detalles Bibliográficos
Autores principales: Furini, Simone, Barbini, Paolo, Domene, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627591/
https://www.ncbi.nlm.nih.gov/pubmed/23430151
http://dx.doi.org/10.1093/nar/gkt099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627591/
https://www.ncbi.nlm.nih.gov/pubmed/23430151
http://dx.doi.org/10.1093/nar/gkt099

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