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DNA-recognition process described by MD simulations of the lactose repressor protein on a specific and a non-specific DNA sequence
The lactose repressor protein may bind DNA in two possible configurations: a specific one, if the DNA sequence corresponds to a binding site, and a non-specific one otherwise. To find its target sequences, the lactose repressor first binds non-specifically to DNA, and subsequently, it rapidly search...
Autores principales: | Furini, Simone, Barbini, Paolo, Domene, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627591/ https://www.ncbi.nlm.nih.gov/pubmed/23430151 http://dx.doi.org/10.1093/nar/gkt099 |
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