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Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases
In T4 bacteriophage, 5-hydroxymethylcytosine (5hmC) is incorporated into DNA during replication. In response, bacteria may have developed modification-dependent type IV restriction enzymes to defend the cell from T4-like infection. PvuRts1I was the first identified restriction enzyme to exhibit spec...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627594/ https://www.ncbi.nlm.nih.gov/pubmed/23482393 http://dx.doi.org/10.1093/nar/gkt102 |