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Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases

In T4 bacteriophage, 5-hydroxymethylcytosine (5hmC) is incorporated into DNA during replication. In response, bacteria may have developed modification-dependent type IV restriction enzymes to defend the cell from T4-like infection. PvuRts1I was the first identified restriction enzyme to exhibit spec...

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Detalles Bibliográficos
Autores principales: Borgaro, Janine G., Zhu, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627594/
https://www.ncbi.nlm.nih.gov/pubmed/23482393
http://dx.doi.org/10.1093/nar/gkt102