The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair

APLF is a forkhead associated-containing protein with poly(ADP-ribose)-binding zinc finger (PBZ) domains, which undergoes ionizing radiation (IR)-induced and Ataxia-Telangiectasia Mutated (ATM)-dependent phosphorylation at serine-116 (Ser(116)). Here, we demonstrate that the phosphorylation of APLF...

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Detalles Bibliográficos
Autores principales: Fenton, Amanda L., Shirodkar, Purnata, Macrae, Chloe J., Meng, Li, Koch, C. Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627606/
https://www.ncbi.nlm.nih.gov/pubmed/23449221
http://dx.doi.org/10.1093/nar/gkt134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627606/
https://www.ncbi.nlm.nih.gov/pubmed/23449221
http://dx.doi.org/10.1093/nar/gkt134

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