Cargando…

Emphasis on the Role of PF4 in the Incidence, Pathophysiology and Treatment of Heparin Induced Thrombocytopenia

Heparin Induced Thrombocytopenia (HIT) is caused by antibodies that recognize platelet factor 4 (PF4) associated with polyanionic glycosaminoglycan drugs or displayed on vascular cell membranes. These antibodies are elicited by multimolecular complexes that can occur when heparin is administered in...

Descripción completa

Detalles Bibliográficos
Autores principales: Prechel, M Margaret, Walenga, Jeanine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627638/
https://www.ncbi.nlm.nih.gov/pubmed/23561460
http://dx.doi.org/10.1186/1477-9560-11-7