Subcellular Localization Determines the Stability and Axon Protective Capacity of Axon Survival Factor Nmnat2

Axons require a constant supply of the labile axon survival factor Nmnat2 from their cell bodies to avoid spontaneous axon degeneration. Here we investigate the mechanism of fast axonal transport of Nmnat2 and its site of action for axon maintenance. Using dual-colour live-cell imaging of axonal tra...

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Detalles Bibliográficos
Autores principales: Milde, Stefan, Gilley, Jonathan, Coleman, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627647/
https://www.ncbi.nlm.nih.gov/pubmed/23610559
http://dx.doi.org/10.1371/journal.pbio.1001539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627647/
https://www.ncbi.nlm.nih.gov/pubmed/23610559
http://dx.doi.org/10.1371/journal.pbio.1001539

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