Electron Tomography Reveals Novel Microtubule Lattice and Microtubule Organizing Centre Defects in +TIP Mutants

Mal3p and Tip1p are the fission yeast (Schizosaccharomyces pombe) homologues of EB1 and CLIP-170, two conserved microtubule plus end tracking proteins (+TIPs). These proteins are crucial regulators of microtubule dynamics. Using electron tomography, we carried out a high-resolution analysis of the p...

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Detalles Bibliográficos
Autores principales: Höög, Johanna L., Huisman, Stephen M., Brunner, Damian, Antony, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627915/
https://www.ncbi.nlm.nih.gov/pubmed/23613905
http://dx.doi.org/10.1371/journal.pone.0061698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627915/
https://www.ncbi.nlm.nih.gov/pubmed/23613905
http://dx.doi.org/10.1371/journal.pone.0061698

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