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Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes
BACKGROUND: Filaggrin (FLG) has a central role in the pathogenesis of atopic dermatitis (AD). FLG is a complex repetitive gene; highly population-specific mutations and multiple rare mutations make routine genotyping complex. Furthermore, the mechanistic pathways through which mutations in FLG predi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mosby
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627961/ https://www.ncbi.nlm.nih.gov/pubmed/20621340 http://dx.doi.org/10.1016/j.jaci.2010.04.038 |