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Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes

BACKGROUND: Filaggrin (FLG) has a central role in the pathogenesis of atopic dermatitis (AD). FLG is a complex repetitive gene; highly population-specific mutations and multiple rare mutations make routine genotyping complex. Furthermore, the mechanistic pathways through which mutations in FLG predi...

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Detalles Bibliográficos
Autores principales:	O'Regan, Gráinne M., Kemperman, Patrick M.J.H., Sandilands, Aileen, Chen, Huijia, Campbell, Linda E., Kroboth, Karin, Watson, Rosemarie, Rowland, Marion, Puppels, Gerwin J., McLean, W.H. Irwin, Caspers, Peter J., Irvine, Alan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mosby 2010
Materias:	Atopic Dermatitis and Skin Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627961/ https://www.ncbi.nlm.nih.gov/pubmed/20621340 http://dx.doi.org/10.1016/j.jaci.2010.04.038

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