Vascular-derived TGF-β increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain

Neurogenesis decreases during aging and following cranial radiotherapy, causing a progressive cognitive decline that is currently untreatable. However, functional neural stem cells remained present in the subventricular zone of high dose-irradiated and aged mouse brains. We therefore investigated wh...

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Detalles Bibliográficos
Autores principales: Pineda, Jose R, Daynac, Mathieu, Chicheportiche, Alexandra, Cebrian-Silla, Arantxa, Sii Felice, Karine, Garcia-Verdugo, Jose Manuel, Boussin, François D, Mouthon, Marc-André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628106/
https://www.ncbi.nlm.nih.gov/pubmed/23526803
http://dx.doi.org/10.1002/emmm.201202197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628106/
https://www.ncbi.nlm.nih.gov/pubmed/23526803
http://dx.doi.org/10.1002/emmm.201202197

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