Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke

EZH2 plays an important role in stem cell renewal and maintenance by inducing gene silencing via its histone methyltransferase activity. Previously, we showed that EZH2 downregulation enhances neuron differentiation of human mesenchymal stem cells (hMSCs); however, the underlying mechanisms of EZH2-...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yung-Luen, Chou, Ruey-Hwang, Shyu, Woei-Cherng, Hsieh, Shu-Ching, Wu, Chen-Shiou, Chiang, Shu-Ya, Chang, Wei-Jung, Chen, Jia-Ni, Tseng, Yen-Ju, Lin, Yu-Hsuan, Lee, Wei, Yeh, Su-Peng, Hsu, Jennifer L, Yang, Cheng-Chieh, Hung, Shih-Chieh, Hung, Mien-Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628108/
https://www.ncbi.nlm.nih.gov/pubmed/23526793
http://dx.doi.org/10.1002/emmm.201201783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628108/
https://www.ncbi.nlm.nih.gov/pubmed/23526793
http://dx.doi.org/10.1002/emmm.201201783

Ejemplares similares