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Paradoxic effects of propofol on visceral pain induced by various TRPV1 agonists

Intraperitoneal injection of propofol inhibits subsequent acetic acid-induced writhing response in mice. Propofol increases the sensitivity of dorsal root ganglion neurons to capsaicin through transient receptor potential ankyrin subtype-1 (TRPA1) and protein kinase Cε (PKCε)-mediated phosphorylatio...

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Detalles Bibliográficos
Autores principales: JI, WENJIN, CUI, CAN, ZHANG, ZHIWEI, LIANG, JIEXIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628225/
https://www.ncbi.nlm.nih.gov/pubmed/23596498
http://dx.doi.org/10.3892/etm.2013.950