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Adenosinergic Depression of Glutamatergic Transmission in the Entorhinal Cortex of Juvenile Rats via Reduction of Glutamate Release Probability and the Number of Releasable Vesicles

Adenosine is an inhibitory neuromodulator that exerts antiepileptic effects in the brain and the entorhinal cortex (EC) is an essential structure involved in temporal lobe epilepsy. Whereas microinjection of adenosine into the EC has been shown to exert powerful antiepileptic effects, the underlying...

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Detalles Bibliográficos
Autores principales: Wang, Shouping, Kurada, Lalitha, Cilz, Nicholas I., Chen, Xiaotong, Xiao, Zhaoyang, Dong, Hailong, Lei, Saobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628342/
https://www.ncbi.nlm.nih.gov/pubmed/23614032
http://dx.doi.org/10.1371/journal.pone.0062185