A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel

Opening of BK-type Ca(2+) activated K(+) channels protects the heart against ischemia-reperfusion (IR) injury. However, the location of BK channels responsible for cardioprotection is debated. Herein we confirmed that openers of the SLO1 BK channel, NS1619 and NS11021, were protective in a mouse per...

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Detalles Bibliográficos
Autores principales: Wojtovich, Andrew P., Nadtochiy, Sergiy M., Urciuoli, William R., Smith, Charles O., Grunnet, Morten, Nehrke, Keith, Brookes, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628382/
https://www.ncbi.nlm.nih.gov/pubmed/23638385
http://dx.doi.org/10.7717/peerj.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628382/
https://www.ncbi.nlm.nih.gov/pubmed/23638385
http://dx.doi.org/10.7717/peerj.48

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