Cargando…
A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel
Opening of BK-type Ca(2+) activated K(+) channels protects the heart against ischemia-reperfusion (IR) injury. However, the location of BK channels responsible for cardioprotection is debated. Herein we confirmed that openers of the SLO1 BK channel, NS1619 and NS11021, were protective in a mouse per...
Autores principales: | Wojtovich, Andrew P., Nadtochiy, Sergiy M., Urciuoli, William R., Smith, Charles O., Grunnet, Morten, Nehrke, Keith, Brookes, Paul S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628382/ https://www.ncbi.nlm.nih.gov/pubmed/23638385 http://dx.doi.org/10.7717/peerj.48 |
Ejemplares similares
-
SLO-2 Is Cytoprotective and Contributes to Mitochondrial Potassium Transport
por: Wojtovich, Andrew P., et al.
Publicado: (2011) -
Single-channel kinetics of BK (Slo1) channels
por: Geng, Yanyan, et al.
Publicado: (2015) -
Heme Regulates Allosteric Activation of the Slo1 BK Channel
por: Horrigan, Frank T., et al.
Publicado: (2005) -
Commentary: A BK (Slo1) channel journey from molecule to physiology
por: Tricarico, Domenico, et al.
Publicado: (2017) -
BK(Ca) (Slo) Channel Regulates Mitochondrial Function and Lifespan in Drosophila melanogaster
por: Gururaja Rao, Shubha, et al.
Publicado: (2019)