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Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase
The BBSome is a complex of seven proteins, including BBS4, that is cycled through cilia by intraflagellar transport (IFT). Previous work has shown that the membrane-associated signaling protein phospholipase D (PLD) accumulates abnormally in cilia of Chlamydomonas reinhardtii bbs mutants. Here we sh...
Autores principales: | Lechtreck, Karl F., Brown, Jason M., Sampaio, Julio L., Craft, Julie M., Shevchenko, Andrej, Evans, James E., Witman, George B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628507/ https://www.ncbi.nlm.nih.gov/pubmed/23589493 http://dx.doi.org/10.1083/jcb.201207139 |
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