Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology

The mammalian target of rapamycin (mTOR) assembles into two distinct multi-protein complexes called mTORC1 and mTORC2. Whereas mTORC1 is known to regulate cell and organismal growth, the role of mTORC2 is less understood. We describe two mouse lines that are devoid of the mTORC2 component rictor in...

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Detalles Bibliográficos
Autores principales: Thomanetz, Venus, Angliker, Nico, Cloëtta, Dimitri, Lustenberger, Regula M., Schweighauser, Manuel, Oliveri, Filippo, Suzuki, Noboru, Rüegg, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628512/
https://www.ncbi.nlm.nih.gov/pubmed/23569215
http://dx.doi.org/10.1083/jcb.201205030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628512/
https://www.ncbi.nlm.nih.gov/pubmed/23569215
http://dx.doi.org/10.1083/jcb.201205030

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