Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia

Notch regulates cell–cell contact-dependent signaling and is activated by hypoxia, a microenvironmental condition that promotes cellular invasion during both normal physiology and disease. The mechanisms by which hypoxia and Notch regulate cellular invasion are not fully elucidated. In this paper, w...

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Detalles Bibliográficos
Autores principales: Díaz, Begoña, Yuen, Angela, Iizuka, Shinji, Higashiyama, Shigeki, Courtneidge, Sara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628517/
https://www.ncbi.nlm.nih.gov/pubmed/23589494
http://dx.doi.org/10.1083/jcb.201209151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628517/
https://www.ncbi.nlm.nih.gov/pubmed/23589494
http://dx.doi.org/10.1083/jcb.201209151

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