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Lipoxin A(4) and 15-Epi-Lipoxin A(4) Protect against Experimental Cerebral Malaria by Inhibiting IL-12/IFN-γ in the Brain

Cerebral malaria is caused by infection with Plasmodium falciparum and can lead to severe neurological manifestations and predominantly affects sub-Saharan African children. The pathogenesis of this disease involves unbalanced over-production of pro-inflammatory cytokines. It is clear that signaling...

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Detalles Bibliográficos
Autores principales: Shryock, Nathaniel, McBerry, Cortez, Salazar Gonzalez, Rosa Maria, Janes, Steven, Costa, Fabio T. M., Aliberti, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628580/
https://www.ncbi.nlm.nih.gov/pubmed/23613965
http://dx.doi.org/10.1371/journal.pone.0061882