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A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ

Cannabinoid receptors (CB) are expressed throughout human skin epithelium. CB1 activation inhibits human hair growth and decreases proliferation of epidermal keratinocytes. Since psoriasis is a chronic hyperproliferative, inflammatory skin disease, it is conceivable that the therapeutic modulation o...

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Detalles Bibliográficos
Autores principales: Ramot, Yuval, Sugawara, Koji, Zákány, Nóra, Tóth, Balázs I., Bíró, Tamás, Paus, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628749/
https://www.ncbi.nlm.nih.gov/pubmed/23638377
http://dx.doi.org/10.7717/peerj.40