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Catechol-O-Methyltransferase (COMT) Protein Expression and Activity after Dopaminergic and Noradrenergic Lesions of the Rat Brain

The occurrence of catechol-O-methyltransferase (COMT) in presynaptic neurons remains controversial. This study utilized dopaminergic and noradrenergic toxins to assess the presence of COMT in the presynaptic neurons originating from the substantia nigra, ventral tegmental area or locus coeruleus. De...

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Detalles Bibliográficos
Autores principales: Schendzielorz, Nadia, Oinas, Juha-Pekka, Myöhänen, Timo T., Reenilä, Ilkka, Raasmaja, Atso, Männistö, Pekka T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628796/
https://www.ncbi.nlm.nih.gov/pubmed/23613844
http://dx.doi.org/10.1371/journal.pone.0061392