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Modulating Gradients in Regulatory Signals within Mesenchymal Stem Cell Seeded Hydrogels: A Novel Strategy to Engineer Zonal Articular Cartilage

Engineering organs and tissues with the spatial composition and organisation of their native equivalents remains a major challenge. One approach to engineer such spatial complexity is to recapitulate the gradients in regulatory signals that during development and maturation are believed to drive spa...

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Detalles Bibliográficos
Autores principales: Thorpe, Stephen D., Nagel, Thomas, Carroll, Simon F., Kelly, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628868/
https://www.ncbi.nlm.nih.gov/pubmed/23613745
http://dx.doi.org/10.1371/journal.pone.0060764