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Quantification of N-acetylcysteamine activated methylmalonate incorporation into polyketide biosynthesis
Polyketides are biosynthesized through consecutive decarboxylative Claisen condensations between a carboxylic acid and differently substituted malonic acid thioesters, both tethered to the giant polyketide synthase enzymes. Individual malonic acid derivatives are typically required to be activated a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628877/ https://www.ncbi.nlm.nih.gov/pubmed/23616811 http://dx.doi.org/10.3762/bjoc.9.75 |