Intraganglionic AAV6 Results in Efficient and Long-Term Gene Transfer to Peripheral Sensory Nervous System in Adult Rats

We previously demonstrated safe and reliable gene transfer to the dorsal root ganglion (DRG) using a direct microinjection procedure to deliver recombinant adeno-associated virus (AAV) vector. In this study, we proceed to compare the in vivo transduction patterns of self-complementary (sc) AAV6 and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Hongwei, Fischer, Gregory, Ferhatovic, Lejla, Fan, Fan, Light, Alan R., Weihrauch, Dorothee, Sapunar, Damir, Nakai, Hiroyuki, Park, Frank, Hogan, Quinn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628918/
https://www.ncbi.nlm.nih.gov/pubmed/23613824
http://dx.doi.org/10.1371/journal.pone.0061266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628918/
https://www.ncbi.nlm.nih.gov/pubmed/23613824
http://dx.doi.org/10.1371/journal.pone.0061266

Ejemplares similares