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Intraganglionic AAV6 Results in Efficient and Long-Term Gene Transfer to Peripheral Sensory Nervous System in Adult Rats
We previously demonstrated safe and reliable gene transfer to the dorsal root ganglion (DRG) using a direct microinjection procedure to deliver recombinant adeno-associated virus (AAV) vector. In this study, we proceed to compare the in vivo transduction patterns of self-complementary (sc) AAV6 and...
Autores principales: | Yu, Hongwei, Fischer, Gregory, Ferhatovic, Lejla, Fan, Fan, Light, Alan R., Weihrauch, Dorothee, Sapunar, Damir, Nakai, Hiroyuki, Park, Frank, Hogan, Quinn H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628918/ https://www.ncbi.nlm.nih.gov/pubmed/23613824 http://dx.doi.org/10.1371/journal.pone.0061266 |
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