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Functional Investigation of NCI-H460-Inducible Myofibroblasts on the Chemoresistance to VP-16 with a Microfluidic 3D Co-Culture Device

Fibroblasts, the major cell type in tumor stroma, are essential for tumor growth and survival, and represent an important therapeutic target for cancers. Here we presented a microfluidic co-culture device in which the three-dimensional (3D) matrix was employed to reconstruct an in vivo-like fibrobla...

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Detalles Bibliográficos
Autores principales: Hao, Yuanyuan, Zhang, Lichuan, He, Jiarui, Guo, Zhe, Ying, Li, Xu, Zhiyun, Zhang, Jianing, Lu, Jianxin, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629031/
https://www.ncbi.nlm.nih.gov/pubmed/23613925
http://dx.doi.org/10.1371/journal.pone.0061754